Set for Life offers different prize levels and winning odds based on the number of matched numbers and the Life Ball. The odds of winning the top prize, which requires 5 numbers plus the Life Ball, are 1 in 15,339,390. The jackpot prize is £10,000 every month for 30 years. The total payout is a whopping £3.6 million over the duration of the prize.
The table below outlines the predetermined and unchanging cash rewards that are guaranteed to winners, regardless of the number of fellow winners, alongside the corresponding winning odds for each distinct prize category:
| Match | Prize | Odds |
| 5 + Life Ball | £10,000 every month for 30 years | 1 in 15,339,390 |
| 5 | £10,000 every month for 1 year | 1 in 1,704,377 |
| 4 + Life Ball | £250 | 1 in 73,045 |
| 4 | £50 | 1 in 8,116 |
| 3 + Life Ball | £30 | 1 in 1,782 |
| 3 | £20 | 1 in 198 |
| 2 + Life Ball | £10 | 1 in 134 |
| 2 | £5 | 1 in 15 |
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